Furious Seasons

January 10, 2008 | By deflv In Object | Comments(0)

Pharmacologic treatment and disease management are not mutually exclusive. Ongoing medication and psychosocial treatment trials should be pursued concurrently in order to engender hope, since some patients may benefit over time or take longer to achieve remission. …. As a long time support person and caregiver I am very well familiar with my spouse’s depressive illness or what I refer to as her MDD ( Major Depressive Disorder ) or TRD ( Treatment Resistant Depression )

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Furious Seasons

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Major Depressive Disorder — NEJM

January 3, 2008 | By deflv In Object | Comments(0)

Although some pathogenetic mechanisms in these cases and in cases of major depressive disorder overlap, a history of mania defines a distinct illness termed bipolar disorder.4 ….. Elevated cortisol levels in depression could increase the risk of coronary artery disease , since cortisol increases visceral fat.64,86 Antidepressant treatment increases the survival rate among patients who become depressed after coronary occlusion.86 Endothelial-cell signaling plays a crucial …

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Major Depressive Disorder — NEJM

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