Major Depressive Disorder — NEJM
Although some pathogenetic mechanisms in these cases and in cases of major depressive disorder overlap, a history of mania defines a distinct illness termed bipolar disorder.4 ….. Elevated cortisol levels in depression could increase the risk of coronary artery disease , since cortisol increases visceral fat.64,86 Antidepressant treatment increases the survival rate among patients who become depressed after coronary occlusion.86 Endothelial-cell signaling plays a crucial …
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Major Depressive Disorder — NEJM
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